Roland E-60 was released the same year (in 2007) its E-50 brother was. It hides the sound core based on the Fantom-X series architecture. E-50 was designed to offer a massive set of functions: a 76-note keyboard features a 64-voice polyphony, a large selection of sounds (guitars, drums, basses, pianos) and an additional drum collection (34 sets), a monochrome touch screen (3D-SG), a large number of buttons (located on the front panel) that provide direct access to the most necessary functions. Besides, this model got the patented "D-Beam" controller.

It also has 2 modes for recording: the "Recorder" function with simple rec/start/stop options and a full-function 16-track sequencer with the possibility of detailed macro/micro editing. All sounds can be processed with such effects as: reverb (8 types), chorus (8 kinds), and 41 types of multi-effects.

E-60 provides functions: Style Converter, which is responsible for creating styles based on MIDI files or songs, guitar mode with guitar sounds, Cover/Makeup Tools for quick parameter change in songs, Music Assistant for automatic selection of sounds and styles for Current songs. In addition, the synthesizer supports video management technology V-Link.